The effect of alcohol on ionizing and non-ionizing drug release from hydrophilic, lipophilic and dual matrix tablets

The aim of this work was to investigate and quantitatively evaluate the effect of presence of alcohol on in vitro release of ionizing and non-ionizing drug from hydrophilic, lipophilic and hydrophilic-lipophilic matrix tablets. The Food and Drug Administration (FDA) recommends in vitro dissolution t...

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Bibliographic Details
Main Authors: Václav Lochař, Alena Komersová, Kevin Matzick, Barbora Slezáková, Martin Bartoš, Jitka Mužíková, Samir Haddouchi
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016419301690