Metabolic determinants of electrical failure in ex-vivo canine model of cardiac arrest: evidence for the protective role of inorganic pyrophosphate.

Metabolic determinants of electrical failure in ex-vivo canine model of cardiac arrest: evidence for the protective role of inorganic pyrophosphate.

Deterioration of ventricular fibrillation (VF) into asystole or severe bradycardia (electrical failure) heralds a fatal outcome of cardiac arrest. The role of metabolism in the timing of electrical failure remains unknown.To determine metabolic factors of early electrical failure in an ex-vivo canin...

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Bibliographic Details
Main Authors: Junko Shibayama, Tyson G Taylor, Paul W Venable, Nathaniel L Rhodes, Ryan B Gil, Mark Warren, Adam R Wende, E Dale Abel, James Cox, Kenneth W Spitzer, Alexey V Zaitsev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3592894?pdf=render

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http://europepmc.org/articles/PMC3592894?pdf=render

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