Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus.

BACKGROUND: Nuclear myosin I (NM1) is a nuclear isoform of the well-known "cytoplasmic" Myosin 1c protein (Myo1c). Located on the 11(th) chromosome in mice, NM1 results from an alternative start of transcription of the Myo1c gene adding an extra 16 amino acids at the N-terminus. Previous s...

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Bibliographic Details
Main Authors: Tomáš Venit, Rastislav Dzijak, Alžběta Kalendová, Michal Kahle, Jana Rohožková, Volker Schmidt, Thomas Rülicke, Birgit Rathkolb, Wolfgang Hans, Alexander Bohla, Oliver Eickelberg, Tobias Stoeger, Eckhard Wolf, Ali Önder Yildirim, Valérie Gailus-Durner, Helmut Fuchs, Martin Hrabě de Angelis, Pavel Hozák
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3623870?pdf=render