10-Acetylirciformonin B, A Sponge Furanoterpenoid, Induces DNA Damage and Apoptosis in Leukemia Cells

10-Acetylirciformonin B, A Sponge Furanoterpenoid, Induces DNA Damage and Apoptosis in Leukemia Cells

10-Acetylirciformonin B, a furanoterpenoid derived from irciformonin B found in a marine sponge, has been reported to possess potent cytotoxic activity against several cancer cell lines. However, the mechanism of its apoptotic activity against human leukemia cells has never been reported. The purpos...

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Bibliographic Details
Main Authors: Fu-Wen Kuo, Mei-Chin Lu, Yuan-Shing Ho, Ping-Jyun Sung, Ying-Chi Du, Ting-Hsuan Kung, Yu-Cheng Chen, Huei-Mei Chen, Mohamed El-Shazly, Wen-Been Chang, Jui-Hsin Su
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:Molecules
Subjects:
10-acetylirciformonin B
apoptosis
DNA damage
sponge
Online Access:http://www.mdpi.com/1420-3049/17/10/11839

Internet

http://www.mdpi.com/1420-3049/17/10/11839

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