Fibroblast Growth Factor 10 and Vertebrate Limb Development

Early limb development requires fibroblast growth factor (Fgf)-mediated coordination between growth and patterning to ensure the proper formation of a functional organ. The apical ectodermal ridge (AER) is a domain of thickened epithelium located at the distal edge of the limb bud that coordinates o...

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Bibliographic Details
Main Authors: Libo Jin, Jin Wu, Saverio Bellusci, Jin-San Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Genetics
Subjects:
AER
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00705/full