Site‐Specific Load‐Induced Expansion of Sca‐1+Prrx1+ and Sca‐1−Prrx1+ Cells in Adult Mouse Long Bone Is Attenuated With Age
ABSTRACT Aging is associated with significant bone loss and increased fracture risk, which has been attributed to a diminished response to anabolic mechanical loading. In adults, skeletal progenitors proliferate and differentiate into bone‐forming osteoblasts in response to increasing mechanical sti...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-09-01
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| Series: | JBMR Plus |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/jbm4.10199 |