Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein.

Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein.

Pleiotropic genetic variants have independent effects on different phenotypes. C-reactive protein (CRP) is associated with several cardiometabolic phenotypes. Shared genetic backgrounds may partially underlie these associations. We conducted a genome-wide analysis to identify the shared genetic back...

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Bibliographic Details
Main Authors: Symen Ligthart, Paul S de Vries, André G Uitterlinden, Albert Hofman, CHARGE Inflammation working group, Oscar H Franco, Daniel I Chasman, Abbas Dehghan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4358943?pdf=render

Internet

http://europepmc.org/articles/PMC4358943?pdf=render

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