Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity.

Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity.

Human bone morphogenetic protein receptor 2 (BMPR2) is essential for BMP signalling and may be involved in the regulation of adipogenesis. The BMPR2 locus has been suggested as target of recent selection in human populations. We hypothesized that BMPR2 might have a role in the pathophysiology of obe...

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Bibliographic Details
Main Authors: Dorit Schleinitz, Nora Klöting, Yvonne Böttcher, Sara Wolf, Kerstin Dietrich, Anke Tönjes, Jana Breitfeld, Beate Enigk, Jan Halbritter, Antje Körner, Michael R Schön, Jost Jenkner, Yu-Hua Tseng, Tobias Lohmann, Miriam Dressler, Michael Stumvoll, Matthias Blüher, Peter Kovacs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3032727?pdf=render

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http://europepmc.org/articles/PMC3032727?pdf=render

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