Dexmedetomidine’s inhibitory effects on acetylcholine release from cholinergic nerves in guinea pig trachea: a mechanism that accounts for its clinical benefit during airway irritation

Abstract Background Airway instrumentation can evoke upper airway reflexes including bronchoconstriction and cough which can cause serious complications including airway trauma, laryngospasm or bronchospasm which may in turn lead to difficulty with ventilation and hypoxemia. These airway events are...

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Bibliographic Details
Main Authors: Maya Mikami, Yi Zhang, Benjamin Kim, Tilla S. Worgall, Harald Groeben, Charles W. Emala
Format: Article
Language:English
Published: BMC 2017-03-01
Series:BMC Anesthesiology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12871-017-0345-z