Brominated indoles from a marine mollusc inhibit inflammation in a murine model of acute lung injury.

New drug leads for the treatment of inflammation are urgently needed. Marine molluscs are widely used as traditional medicines for the treatment of inflammation. Here we report the positive effects of a hypobranchial gland (HBG) extract and the dominant bioactive compound 6-bromoisatin from the Muri...

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Bibliographic Details
Main Authors: Tarek B Ahmad, David Rudd, Kirsten Benkendorff, Layla K Mahdi, Kaylah-Ann Pratt, Leanne Dooley, Chuanyu Wei, Michael Kotiw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5658094?pdf=render