Maprotiline inhibits LPS-induced expression of adhesion molecules (ICAM-1 and VCAM-1) in human endothelial cells

Maprotiline inhibits LPS-induced expression of adhesion molecules (ICAM-1 and VCAM-1) in human endothelial cells

Regardless of the known anti-inflammatory potential of heterocyclic antidepressants, the mechanisms concerning their modulating effects are not completely known. In our earlier work, maprotiline, a heterocyclic antidepressants, considerably inhibited infiltration of polymorphonuclear cell leucocytes...

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Bibliographic Details
Main Authors: Laleh Rafiee, Valiollah Hajhashemi, Shaghayegh Haghjooy Javanmard
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
Maprotiline; ICAM-1; VCAM-1; Endothelial cells
Online Access:http://www.jrps.ir/article.asp?issn=1735-5362;year=2016;volume=11;issue=2;spage=138;epage=144;aulast=Rafiee

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http://www.jrps.ir/article.asp?issn=1735-5362;year=2016;volume=11;issue=2;spage=138;epage=144;aulast=Rafiee

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