In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins

Coronavirus (CoV) replication and transcription are carried out in close proximity to restructured endoplasmic reticulum (ER) membranes in replication/transcription complexes (RTC). Many of the CoV nonstructural proteins (nsps) are required for RTC function; however, not all of their functions are k...

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Bibliographic Details
Main Authors: Jeremiah Athmer, Anthony R. Fehr, Matthew Grunewald, Everett Clinton Smith, Mark R. Denison, Stanley Perlman, Peter Palese
Format: Article
Language:English
Published: American Society for Microbiology 2017-01-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/1/e02320-16