Polysialic acid modification of the synaptic cell adhesion molecule SynCAM 1 in human embryonic stem cell-derived oligodendrocyte precursor cells

Oligodendrocyte precursor cells (OPCs) are the progenitors of myelinating oligodendrocytes in brain development and repair. Successful myelination depends on the control of adhesiveness during OPC migration and axon contact formation. The decoration of cell surface proteins with the glycan polysiali...

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Bibliographic Details
Main Authors: Sebastian Werneburg, Falk F.R. Buettner, Martina Mühlenhoff, Herbert Hildebrandt
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506115000410