Comprehensive molecular profiling to predict clinical outcomes in pancreatic cancer
Background: Pancreatic ductal adenocarcinoma (PDAC) has the worst prognosis among common cancers. The genomic landscape of PDAC is defined by four mutational pathways: kirsten rat sarcoma virus ( KRAS), cellular tumor antigen p53 ( TP53 ), cyclin dependent kinase inhibitor 2A ( CDKN2A ), and SMAD fa...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2021-08-01
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Series: | Therapeutic Advances in Medical Oncology |
Online Access: | https://doi.org/10.1177/17588359211038478 |