Cation selectivity of the presequence translocase channel Tim23 is crucial for efficient protein import

Cation selectivity of the presequence translocase channel Tim23 is crucial for efficient protein import

Virtually all mitochondrial matrix proteins and a considerable number of inner membrane proteins carry a positively charged, N-terminal presequence and are imported by the TIM23 complex (presequence translocase) located in the inner mitochondrial membrane. The voltage-regulated Tim23 channel constit...

Full description

Bibliographic Details
Main Authors: Niels Denkert, Alexander Benjamin Schendzielorz, Mariam Barbot, Lennart Versemann, Frank Richter, Peter Rehling, Michael Meinecke
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
mitochondria
protein trafficking
Tim23
electrophysiology
mitochondrial biogenesis
membrane channels
Online Access:https://elifesciences.org/articles/28324

Internet

https://elifesciences.org/articles/28324

Similar Items