Epidermal stem cells maintain stemness via a biomimetic micro/nanofiber scaffold that promotes wound healing by activating the Notch signaling pathway

Epidermal stem cells maintain stemness via a biomimetic micro/nanofiber scaffold that promotes wound healing by activating the Notch signaling pathway

Abstract Background Epidermal stem cells (EpSCs) play a vital role in wound healing and skin renewal. Although biomaterial scaffolds have been used for transplantation of EpSCs in wound healing, the ex vivo differentiation of EpSCs limits their application. Methods To inhibit the differentiation of...

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Bibliographic Details
Main Authors: Zhixiao Lin, Congying Zhao, Zhanjun Lei, Yuheng Zhang, Rong Huang, Bin Lin, Yuchen Dong, Hao Zhang, Jinqing Li, Xueyong Li
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Stem Cell Research & Therapy
Subjects:
Epidermal stem cell
Micro/nanofiber scaffold
Cell differentiation
Wound healing
Notch pathway
Online Access:https://doi.org/10.1186/s13287-021-02418-2

Internet

https://doi.org/10.1186/s13287-021-02418-2

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