The Effects of Icariin on Enhancing Motor Recovery Through Attenuating Pro-inflammatory Factors and Oxidative Stress via Mitochondrial Apoptotic Pathway in the Mice Model of Spinal Cord Injury

The Effects of Icariin on Enhancing Motor Recovery Through Attenuating Pro-inflammatory Factors and Oxidative Stress via Mitochondrial Apoptotic Pathway in the Mice Model of Spinal Cord Injury

Spinal cord injury (SCI) is a severe medical problem leading to crucial life change. Icariin (ICA) is a natural flavonoid compound extracted from the Chinese herb Epimedium brevicornum which has neuroprotective effects. But little is known about the relationship between ICA and SCI. We hypothesized...

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Bibliographic Details
Main Authors: Haotian Li, Xinran Zhang, Xu Zhu, Xi Qi, Kaili Lin, Liming Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Physiology
Subjects:
spinal cord injury
icariin
mitochondria
apoptosis
oxidative stress
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01617/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01617/full

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