The Herbal Combination CPA4-1 Inhibits Changes in Retinal Capillaries and Reduction of Retinal Occludin in db/db Mice

The Herbal Combination CPA4-1 Inhibits Changes in Retinal Capillaries and Reduction of Retinal Occludin in db/db Mice

Increased formation of advanced glycation end products (AGEs) plays an important role in the development of diabetic retinopathy (DR) via blood-retinal barrier (BRB) dysfunction, and reduction of AGEs has been suggested as a therapeutic target for DR. In this study, we examined whether CPA4-1, a her...

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Bibliographic Details
Main Authors: Young Sook Kim, Junghyun Kim, Chan-Sik Kim, Ik Soo Lee, Kyuhyung Jo, Dong Ho Jung, Yun Mi Lee, Jin Sook Kim
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Antioxidants
Subjects:
diabetic retinopathy
db/db mice
Cinnamomi Ramulus
Paeoniae Radix
CPA4-1
blood-retinal barrier
Online Access:https://www.mdpi.com/2076-3921/9/7/627

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https://www.mdpi.com/2076-3921/9/7/627

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