Vascular endothelial growth factor promotes atrial arrhythmias by inducing acute intercalated disk remodeling

Abstract Atrial fibrillation (AF) is the most common arrhythmia and is associated with inflammation. AF patients have elevated levels of inflammatory cytokines known to promote vascular leak, such as vascular endothelial growth factor A (VEGF). However, the contribution of vascular leak and conseque...

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Bibliographic Details
Main Authors: Louisa Mezache, Heather L. Struckman, Amara Greer-Short, Stephen Baine, Sándor Györke, Przemysław B. Radwański, Thomas J. Hund, Rengasayee Veeraraghavan
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77562-5