t-DARPP regulates phosphatidylinositol-3-kinase-dependent cell growth in breast cancer

<p>Abstract</p> <p>Background</p> <p>Recent reports have shown that t-DARPP (truncated isoform of DARPP-32) can mediate trastuzumab resistance in breast cancer cell models. In this study, we evaluated expression of t-DARPP in human primary breast tumors, and investigate...

Full description

Bibliographic Details
Main Authors: Vangamudi Bhavatarini, Peng Dun-Fa, Cai Qiuyin, El-Rifai Wael, Zheng Wei, Belkhiri Abbes
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/240