NLRP3 Inflammasome Signaling as a Link Between HIV-1 Infection and Atherosclerotic Cardiovascular Disease

36.9 million people worldwide are living with HIV-1. The disease remains incurable and HIV-infected patients have increased risk of atherosclerosis. Inflammation is a key driver of atherosclerosis, but no targeted molecular therapies have been developed to reduce cardiovascular risk in people with H...

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Bibliographic Details
Main Authors: Caroline Mullis, Talia H. Swartz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
HIV
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2020.00095/full