Novel modeling of combinatorial miRNA targeting identifies SNP with potential role in bone density.

MicroRNAs (miRNAs) are post-transcriptional regulators that bind to their target mRNAs through base complementarity. Predicting miRNA targets is a challenging task and various studies showed that existing algorithms suffer from high number of false predictions and low to moderate overlap in their pr...

Full description

Bibliographic Details
Main Authors: Claudia Coronnello, Ryan Hartmaier, Arshi Arora, Luai Huleihel, Kusum V Pandit, Abha S Bais, Michael Butterworth, Naftali Kaminski, Gary D Stormo, Steffi Oesterreich, Panayiotis V Benos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23284279/pdf/?tool=EBI