Activity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1

Summary: Homeostatic synaptic downscaling reduces neuronal excitability by modulating the number of postsynaptic receptors. Histone modifications and the subsequent chromatin remodeling play critical roles in activity-dependent gene expression. Histone modification codes are recognized by chromatin...

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Bibliographic Details
Main Authors: Wenjie Mao, Anna C. Salzberg, Motokazu Uchigashima, Yuto Hasegawa, Hanno Hock, Masahiko Watanabe, Schahram Akbarian, Yuka Imamura Kawasawa, Kensuke Futai
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718307745