Inclusion complex of S(-) bupivacaine and 2-hydroxypropyl- -cyclodextrin: study of morphology and cytotoxicity

Inclusion complex of S(-) bupivacaine and 2-hydroxypropyl- -cyclodextrin: study of morphology and cytotoxicity

Local anesthetics (LA) belong to a class of pharmacological compounds that attenuate or eliminate pain by binding to the sodium channel of excitable membranes, blocking the influx of sodium ions and the propagation of the nerve impulse. S (-) bupivacaine (S(-) bvc) is a local anesthetic of amino-ami...

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Bibliographic Details
Main Authors: C.M. Moraes, D.R. Araújo, M.G. Issa, H.G. Ferraz, F. Yokaichiya, M.K.K.D. Franco, I. Mazzaro, P.S. Lopes, M.M. Gonçalves, E. de Paula, L.F. Fraceto
Format: Article
Language:English
Published: São Paulo State University (UNESP) 2006-09-01
Series:Revista de Ciências Farmacêuticas Básica e Aplicada
Subjects:
s(-) bupivacaine; cyclodextrin; inclusion complex.
Online Access:http://rcfba.fcfar.unesp.br/index.php/ojs/article/view/548

Internet

http://rcfba.fcfar.unesp.br/index.php/ojs/article/view/548

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