Regulation of ABCA1 expression in human keratinocytes and murine epidermis

Keratinocytes require abundant cholesterol for cutaneous permeability barrier function; hence, the regulation of cholesterol homeostasis is of great importance. ABCA1 is a membrane transporter responsible for cholesterol efflux and plays a pivotal role in regulating cellular cholesterol levels. We d...

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Bibliographic Details
Main Authors: Yan J. Jiang, Biao Lu, Peggy Kim, Peter M. Elias, Kenneth R. Feingold
Format: Article
Language:English
Published: Elsevier 2006-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520434121