<i>Bifidobacterium bifidum</i> Enhances the Intestinal Epithelial Tight Junction Barrier and Protects against Intestinal Inflammation by Targeting the Toll-like Receptor-2 Pathway in an NF-κB-Independent Manner

<i>Bifidobacterium bifidum</i> Enhances the Intestinal Epithelial Tight Junction Barrier and Protects against Intestinal Inflammation by Targeting the Toll-like Receptor-2 Pathway in an NF-κB-Independent Manner

Defective intestinal tight junction (TJ) barrier is a hallmark in the pathogenesis of inflammatory bowel disease (IBD). To date, there are no effective therapies that specifically target the intestinal TJ barrier. Among the various probiotic bacteria, <i>Bifidobacterium</i>, is one of th...

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Bibliographic Details
Main Authors: Rana Al-Sadi, Viszwapriya Dharmaprakash, Prashant Nighot, Shuhong Guo, Meghali Nighot, Toan Do, Thomas Y. Ma
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Bifidobacterium</i>
intestinal barrier
toll-like receptor-2
Online Access:https://www.mdpi.com/1422-0067/22/15/8070

Internet

https://www.mdpi.com/1422-0067/22/15/8070

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