Epstein-Barr Virus Latent Membrane Protein 1 Regulates Host B Cell MicroRNA-155 and Its Target FOXO3a via PI3K p110α Activation

Epstein-Barr Virus Latent Membrane Protein 1 Regulates Host B Cell MicroRNA-155 and Its Target FOXO3a via PI3K p110α Activation

Epstein-Barr Virus (EBV) is associated with potentially fatal lymphoproliferations such as post-transplant lymphoproliferative disorder (PTLD), a serious complication of transplantation. The viral mechanisms underlying the development and maintenance of EBV+ B cell lymphomas remain elusive but repre...

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Bibliographic Details
Main Authors: Olivia Hatton, Madeline M. Smith, Madison Alexander, Melanie Mandell, Carissa Sherman, Madeline W. Stesney, Sin Ting Hui, Gillian Dohrn, Joselinne Medrano, Kurt Ringwalt, Aleishia Harris-Arnold, Eden M. Maloney, Sheri M. Krams, Olivia M. Martinez
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Microbiology
Subjects:
Epstein-Barr virus
latent membrane protein 1
microRNA
miR-155
FOXO3a
PI3K
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02692/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02692/full

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