Generating Aptamers by Cell-SELEX for Applications in Molecular Medicine

Generating Aptamers by Cell-SELEX for Applications in Molecular Medicine

Aptamers are single-stranded oligonucleotides of DNA or RNA that bind to target molecules with high affinity and specificity. Typically, aptamers are generated by an iterative selection process, called systematic evolution of ligands by exponential enrichment (SELEX). Recent advancements in SELEX te...

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Bibliographic Details
Main Authors: Huixia Liu, Xielan Zhao, Weihong Tan, Jun Liu, Minyuan Peng, Jing Liu, Jun Hu, Mao Ye
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:International Journal of Molecular Sciences
Subjects:
aptamer
SELEX
molecular medicine
Online Access:http://www.mdpi.com/1422-0067/13/3/3341/

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http://www.mdpi.com/1422-0067/13/3/3341/

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