Removal of Endotoxin from rAAV Samples Using a Simple Detergent-Based Protocol

Endotoxin is the most common contaminant found in protein samples. Even a small amount of endotoxin can induce strong allergic reaction and death of a host organism. Endotoxin is also often detected in recombinant adeno-associated virus (rAAV) stocks prepared in research laboratories using off-the-s...

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Bibliographic Details
Main Authors: Liudmyla Kondratova, Oleksandr Kondratov, Ragy Ragheb, Sergei Zolotukhin
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050119300932