Enhanced anticancer activity of gemcitabine in combination with noscapine via antiangiogenic and apoptotic pathway against non-small cell lung cancer.

BACKGROUND:The aim of this investigation was to evaluate the anticancer activity of Noscapine (Nos) and Gemcitabine (Gem) combination (NGC) against non-small cell lung cancer (NSCLC) and to elucidate the underlying mechanism of action. METHODS:Isobolographic method was used to calculate combination...

Full description

Bibliographic Details
Main Authors: Mahavir B Chougule, Apurva Patel, Pratik Sachdeva, Tanise Jackson, Mandip Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3216931?pdf=render