A novel CpG island set identifies tissue-specific methylation at developmental gene loci.

A novel CpG island set identifies tissue-specific methylation at developmental gene loci.

CpG islands (CGIs) are dense clusters of CpG sequences that punctuate the CpG-deficient human genome and associate with many gene promoters. As CGIs also differ from bulk chromosomal DNA by their frequent lack of cytosine methylation, we devised a CGI enrichment method based on nonmethylated CpG aff...

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Bibliographic Details
Main Authors: Robert Illingworth, Alastair Kerr, Dina Desousa, Helle Jørgensen, Peter Ellis, Jim Stalker, David Jackson, Chris Clee, Robert Plumb, Jane Rogers, Sean Humphray, Tony Cox, Cordelia Langford, Adrian Bird
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18232738/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18232738/?tool=EBI

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