Genome-wide assessment of differential translations with ribosome profiling data

The global measurement of ribosome occupancy on mRNAs is commonly used as a proxy in estimating rates of protein synthesis. Here the authors describe Xtail, a computational approach that facilitates the extraction of accurate quantitative insight from ribosome profiling data (Ribo-Seq).

Bibliographic Details
Main Authors: Zhengtao Xiao, Qin Zou, Yu Liu, Xuerui Yang
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11194