coTRaCTE predicts co-occurring transcription factors within cell-type specific enhancers.

Cell-type specific gene expression is regulated by the combinatorial action of transcription factors (TFs). In this study, we predict transcription factor (TF) combinations that cooperatively bind in a cell-type specific manner. We first divide DNase hypersensitive sites into cell-type specifically...

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Bibliographic Details
Main Authors: Alena van Bömmel, Michael I Love, Ho-Ryun Chung, Martin Vingron
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC6126874?pdf=render