Radiosynthesis and in vivo evaluation of 11C-labeled BMS-193885 and its desmethyl analog as PET tracers for neuropeptide Y1 receptors

Radiosynthesis and in vivo evaluation of 11C-labeled BMS-193885 and its desmethyl analog as PET tracers for neuropeptide Y1 receptors

Abstract Background Neuropeptide Y (NPY) has been implicated in a wide variety of physiological processes, including feeding, learning, memory, emotion, cardiovascular homeostasis, hormone secretion, and circadian rhythms. NPY Yl receptor (NPY Y1-R) is the most widely studied NPY receptor, and is in...

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Bibliographic Details
Main Authors: Kazunori Kawamura, Wakana Mori, Masayuki Fujinaga, Tomoteru Yamasaki, Yiding Zhang, Hidekatsu Wakizaka, Akiko Hatori, Lin Xie, Katsushi Kumata, Takayuki Ohkubo, Yusuke Kurihara, Masanao Ogawa, Nobuki Nengaki, Ming-Rong Zhang
Format: Article
Language:English
Published: SpringerOpen 2019-02-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Carbon-11
Positron emission tomography
Neuropeptide Y1 receptor
BMS-193885
Online Access:http://link.springer.com/article/10.1186/s41181-019-0056-5

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http://link.springer.com/article/10.1186/s41181-019-0056-5

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