Modulation of Innate Immunity by lignin-Carbohydrate, a Novel TLR4 Ligand, Results in Augmentation of Mucosal IgA and Systemic IgG Production

Modulation of Innate Immunity by lignin-Carbohydrate, a Novel TLR4 Ligand, Results in Augmentation of Mucosal IgA and Systemic IgG Production

Previous study revealed that a specific lignin-carbohydrate preparation, named as lignin-rich enzyme lignin (LREL) derived from plant husk, is a novel toll-like receptor 4 ligand and shows a potent immune-stimulatory activity against dendritic cells (DCs) in vitro. In this report, we investigated im...

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Bibliographic Details
Main Authors: Ryohei Tsuji, Kumiko Ikado, Daisuke Fujiwara
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:International Journal of Molecular Sciences
Subjects:
lignin-carbohydrate
innate immunity
dendritic cell
Toll-like receptor 4 (TLR4)
mucosal immunology
immunoglobulin A (IgA)
vaccine adjuvant
Online Access:https://www.mdpi.com/1422-0067/19/1/64

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https://www.mdpi.com/1422-0067/19/1/64

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