Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice

Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice

Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of middle-aged to old individuals. The pathophysiological process of AD is believed to begin many years before the emergence of clinical symptoms. The important influence of congenital genetic aberrations on the...

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Bibliographic Details
Main Authors: Wei Wei, Yifan Wang, Yinghua Liu, Chun-Ling Dai, Yunn-Chyn Tung, Fei Liu, Khalid Iqbal
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Ciliary neurotrophic factor (CNTF)–derived peptide
Cognition
Amyloid-β
Tau pathology
Neuroplasticity
Online Access:http://link.springer.com/article/10.1186/s13195-020-00666-7

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http://link.springer.com/article/10.1186/s13195-020-00666-7

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