Mutational Spectrum of Multiple Endocrine Neoplasia Type 2 and Sporadic Medullary Thyroid Carcinoma in Taiwan

Mutational Spectrum of Multiple Endocrine Neoplasia Type 2 and Sporadic Medullary Thyroid Carcinoma in Taiwan

Multiple endocrine neoplasia type 2 (MEN 2) is an autosomal dominant cancer predisposition syndrome, and > 95% of MEN 2 patients carry rearranged during transfection (RET) protooncogene mutants. We aimed to elucidate the genotype and phenotype relationship of RET proto-oncogene mutations in Taiwa...

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Bibliographic Details
Main Authors: Chin-Feng Chang, Wei-Shiung Yang, Yi-Ning Su, I-Ling Wu, Tien-Chun Chang
Format: Article
Language:English
Published: Elsevier 2009-05-01
Series:Journal of the Formosan Medical Association
Subjects:
human
multiple endocrine neoplasia type 2A
multiple endocrine neoplasia type 2B
mutation
RET protein
thyroid neoplasms
Online Access:http://www.sciencedirect.com/science/article/pii/S092966460960084X

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http://www.sciencedirect.com/science/article/pii/S092966460960084X

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