A low fish oil inhibits SREBP-1 proteolytic cascade, while a high-fish-oil feeding decreases SREBP-1 mRNA in mice liver: relationship to anti-obesity

A low fish oil inhibits SREBP-1 proteolytic cascade, while a high-fish-oil feeding decreases SREBP-1 mRNA in mice liver: relationship to anti-obesity

Rodents fed fish oil showed less obesity with a reduction of triglyceride synthesis in liver, relative to other dietary oils, along with a decrease of mature form of sterol regulatory element binding protein-1 (SREBP-1) and activation of peroxisome proliferator-activated receptor α (PPARα). Decrease...

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Bibliographic Details
Main Authors: Teruyo Nakatani, Hyoun-Ju Kim, Yasushi Kaburagi, Kazuki Yasuda, Osamu Ezaki
Format: Article
Language:English
Published: Elsevier 2003-02-01
Series:Journal of Lipid Research
Subjects:
n-3 fatty acids
dual-energy X-ray absorptiometry
stearoyl-CoA desaturase
fatty acid synthase
acetyl-CoA carboxylase
acyl-CoA oxidase
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520312244

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http://www.sciencedirect.com/science/article/pii/S0022227520312244

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