Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin

Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin

Unlike the majority of actinomycete secondary metabolic pathways, the biosynthesis of peptidoglycan glycosyltransferase inhibitor moenomycin in Streptomyces ghanaensis does not involve any cluster-situated regulators (CSRs). This raises questions about the regulatory signals that initiate and sustai...

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Bibliographic Details
Main Authors: Roman Makitrynskyy, Bohdan Ostash, Olga Tsypik, Yuriy Rebets, Emma Doud, Timothy Meredith, Andriy Luzhetskyy, Andreas Bechthold, Suzanne Walker, Victor Fedorenko
Format: Article
Language:English
Published: The Royal Society 2013-01-01
Series:Open Biology
Subjects:
pleiotropic regulators
streptomyces
moenomycin a
adpa
blda
absb
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130121

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https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130121

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