CHAF1B induces radioresistance by promoting DNA damage repair in nasopharyngeal carcinoma

CHAF1B induces radioresistance by promoting DNA damage repair in nasopharyngeal carcinoma

Background: Radiotherapy is the main treatment for nasopharyngeal carcinoma (NPC); however radioresistance restricts its efficacy. Therefore, new molecular regulators are required to improve the radiosensitivity of NPC. Chromatin assembly factor 1 subunit B (CHAF1B) plays a role in DNA synthesis and...

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Bibliographic Details
Main Authors: Muping Di, Meng Wang, Jingjing Miao, Boyu Chen, Huageng Huang, Chuyong Lin, Yunting Jian, Yue Li, Ying Ouyang, Xiangfu Chen, Lin Wang, Chong Zhao
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
CHAF1B
Nasopharyngeal carcinoma
DNA damage repair
Radioresistance
DNA-PK pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219353703

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http://www.sciencedirect.com/science/article/pii/S0753332219353703

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