ATPase-dependent control of the Mms21 SUMO ligase during DNA repair.

ATPase-dependent control of the Mms21 SUMO ligase during DNA repair.

Modification of proteins by SUMO is essential for the maintenance of genome integrity. During DNA replication, the Mms21-branch of the SUMO pathway counteracts recombination intermediates at damaged replication forks, thus facilitating sister chromatid disjunction. The Mms21 SUMO ligase docks to the...

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Bibliographic Details
Main Authors: Marcelino Bermúdez-López, Irene Pociño-Merino, Humberto Sánchez, Andrés Bueno, Clàudia Guasch, Seba Almedawar, Sergi Bru-Virgili, Eloi Garí, Claire Wyman, David Reverter, Neus Colomina, Jordi Torres-Rosell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.1002089

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https://doi.org/10.1371/journal.pbio.1002089

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