A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins

A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins

Yeast Sfh5 is an unusual member of the Sec14-like phosphatidylinositol transfer protein (PITP) family. Whereas PITPs are defined by their abilities to transfer phosphatidylinositol between membranes in vitro, and to stimulate phosphoinositide signaling in vivo, Sfh5 does not exhibit these activities...

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Bibliographic Details
Main Authors: Danish Khan, Dongju Lee, Gulcin Gulten, Anup Aggarwal, Joshua Wofford, Inna Krieger, Ashutosh Tripathi, John W Patrick, Debra M Eckert, Arthur Laganowsky, James Sacchettini, Paul Lindahl, Vytas A Bankaitis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-08-01
Series:eLife
Subjects:
Candida
lipid signaling
phosphoinositides
PITPs
heme
Sfh5
Online Access:https://elifesciences.org/articles/57081

Internet

https://elifesciences.org/articles/57081

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