Hypohidrotic ectodermal dysplasia and immunodeficiency with coincident NEMO and EDA Mutations

Hypohidrotic ectodermal dysplasia and immunodeficiency with coincident NEMO and EDA Mutations

Ectodermal dysplasias (ED) are uncommon genetic disorders resulting in abnormalities in ectodermally-derived structures. Though many ED-associated genes have been described, the NF-κB Essential Modulator (NEMO encoded by the IKBKG gene) is unique in that mutations also result in severe humoral and...

Full description

Bibliographic Details
Main Authors: Michael D. Keller, Maureen ePetersen, Peck eOng, Joseph eChurch, Kimberly eRisma, Jon eBurnham, Ashish eJain, E. Richard Stiehm, Eric P. Hanson, Gulbu eUzel, Matthew A. Deardorff, Jordan S. Orange
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-11-01
Series:Frontiers in Immunology
Subjects:
Ectodermal Dysplasia
immunodeficiency
EDA
NEMO
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00061/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00061/full

Similar Items