Adeno-Associated Viral Delivery of GDNF Promotes Recovery of Dopaminergic Phenotype following a Unilateral 6-Hydroxydopamine Lesion

Glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor for dopamine neurons that has been proposed for use in the treatment of Parkinson's disease (PD). Previous studies using viral vectors to deliver GDNF in rodent models of PD have entailed administering the virus...

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Bibliographic Details
Main Authors: John Mcgrath, Elishia Lintz, Barry J. Hoffer, Greg A. Gerhardt, E. Matthew Quintero, Ann-Charlotte Granholm Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2002-04-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096020198389988