Downregulation of CXXC Finger Protein 4 Leads to a Tamoxifen-resistant Phenotype in Breast Cancer Cells Through Activation of the Wnt/β-catenin Pathway

Tamoxifen is a successful endocrine therapy drug for estrogen receptor–positive (ER+) breast cancer. However, resistance to tamoxifen compromises the efficacy of endocrine treatment. In the present study, we identified potential tamoxifen resistance–related gene markers and investigated their mechan...

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Bibliographic Details
Main Authors: Yijie Fu, Zhu Wang, Chuanxu Luo, Yu Wang, Yanping Wang, Xiaorong Zhong, Hong Zheng
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523319304401