Stereoselective syntheses of (+)- isoretronecanol and (+)-5-epi-tashiromine via addition of chiral titanium (iv) enolates to cyclic n-acyliminium ions

Stereoselective syntheses of (+)- isoretronecanol and (+)-5-epi-tashiromine via addition of chiral titanium (iv) enolates to cyclic n-acyliminium ions

The stereoselective addition of the titanium (IV) enolates derived from (S)-4-isopropyl-N-4-chlorobutyryl-1,3-thiazolidine-2-thione (8) and from (S)-4-isopropyl-N-4-chloropentanoyl-1,3-thiazolidine-2-thione (9) to N-Boc-2-methoxypyrrolidine (5b) afforded the addition products (+)-10 and (+)-11 in 84...

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Bibliographic Details
Main Authors: Elaine Pereira, Conceição de Fátima Alves, Maria Alice Böckelmann, Ronaldo A. Pilli
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2008-01-01
Series:Química Nova
Subjects:
(+)-isoretronecanol
(+)-5-epi-tashiromine
asymmetric synthesis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000400012

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000400012

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