Identification and Phenotype of MAIT Cells in Cattle and Their Response to Bacterial Infections

Mucosal-associated invariant T (MAIT) cells are a population of innate-like T cells that utilize a semi-invariant T cell receptor (TCR) α chain and are restricted by the highly conserved antigen presenting molecule MR1. MR1 presents microbial riboflavin biosynthesis derived metabolites produced by b...

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Bibliographic Details
Main Authors: Matthew D. Edmans, Timothy K. Connelley, Siddharth Jayaraman, Christina Vrettou, Martin Vordermeier, Jeffrey Y. W. Mak, Ligong Liu, David P. Fairlie, Emmanuel Atangana Maze, Tiphany Chrun, Paul Klenerman, Sidonia B. G. Eckle, Elma Tchilian, Lindert Benedictus
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.627173/full