Investigating gene expression profiles of whole blood and peripheral blood mononuclear cells using multiple collection and processing methods.

Gene expression profiling using blood samples is a valuable tool for biomarker discovery in clinical studies. Different whole blood RNA collection and processing methods are highly variable and might confound comparisons of results across studies. The main aim of the current study is to compare how...

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Bibliographic Details
Main Authors: Aarti Gautam, Duncan Donohue, Allison Hoke, Stacy Ann Miller, Seshamalini Srinivasan, Bintu Sowe, Leanne Detwiler, Jesse Lynch, Michael Levangie, Rasha Hammamieh, Marti Jett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225137