Mesenchymal Stem Cells Attenuate Acute Liver Failure by Promoting Expansion of Regulatory T Cells in an Indoleamine 2,3-Dioxygenase-Dependent Manner

Mesenchymal Stem Cells Attenuate Acute Liver Failure by Promoting Expansion of Regulatory T Cells in an Indoleamine 2,3-Dioxygenase-Dependent Manner

The influence of mesenchymal stem cells (MSCs) on the phenotype and function of CD4+CD49b+FoxP3- regulatory cells has not been elucidated. We used Concanavalin A (ConA) - and α-galactosylceramide (α-GalCer)-induced acute liver injury to estimate the effects of MSCs on liver-infiltrating CD4+CD49b+Fo...

Full description

Bibliographic Details
Main Authors: Miloradovic Dragana, Miloradovic Dragica, Jankovic Marina Gazdic, Markovic Bojana Simovic, Harrell C. Randall, Fellabaum Crissy, Arsenijevic Nebojsa, Lukic Aleksandra, Volarevic Vladislav
Format: Article
Language:English
Published: Sciendo 2020-09-01
Series:Serbian Journal of Experimental and Clinical Research
Subjects:
mesenchymal stem cells
regulatory t cells
acute liver failure
Online Access:https://doi.org/10.2478/sjecr-2018-0043

Internet

https://doi.org/10.2478/sjecr-2018-0043

Similar Items