Structures and dynamics of the novel S1/S2 protease cleavage site loop of the SARS-CoV-2 spike glycoprotein
At the end of 2019, a new highly virulent coronavirus known under the name SARS-CoV-2 emerged as a human pathogen. One key feature of SARS-CoV-2 is the presence of an enigmatic insertion in the spike glycoprotein gene representing a novel multibasic S1/S2 protease cleavage site. The proteolytic clea...
Main Authors: | Thomas Lemmin, David Kalbermatter, Daniel Harder, Philippe Plattet, Dimitrios Fotiadis |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | Journal of Structural Biology: X |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590152420300209 |
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